Owlpen Manor is a mile east of Uley, off the B4066. At the small Green past the Old Crown pub in Uley (just opposite the Church), you will see OWLPEN signposted, one mile.
Uley is a charming Cotswold Edge village set in spectacular countryside between Tetbury, Stroud (both 6 miles) and Dursley (3 miles west), signposted from the A 4135.
The M5 Junctions 13 (north) and 14 (south) are a few minutes west of Owlpen: head for the B4066.
The M4 is 12 miles south. Exit at Junction 18 and follow the A46 north in the direction of Stroud as far as the crossroads with the A4135. Then go west towards Dursley, turning second right after the Hunters' Hall pub in Kingscote down to village of Uley on B4066. Turn right into the village and at the green by the Old Crown pub follow signs to Owlpen.
The satnav system [postcode GL11 5BZ] may lead you down the steep lane (1 in 4) which passes in front (south) of the house.
Central London is about 2 hours away; Heathrow Airport a little closer.